Central Dysmyelination Reduces the Temporal Fidelity of Synaptic Transmission and 2 the Reliability of Postsynaptic Firing during High-frequency Stimulation. 3 4
نویسندگان
چکیده
1 1 Central dysmyelination reduces the temporal fidelity of synaptic transmission and 2 the reliability of postsynaptic firing during high-frequency stimulation. 3 4 Sei Eun Kim, Karl Turkington, Christopher Kushmerick and Jun Hee Kim 5 6 The Department of Physiology, University of Texas Health Science Center, San 7 Antonio, Texas 78229, USA 8 Departamento de Fisiologia e Biofisica, Universidade Federal de Minas Gerais, Belo 9 Horizonte, 31270–901, Minas Gerais, Brazil 10 11 Corresponding author: Jun Hee Kim, Ph.D. ([email protected]) 12 13 The number of pages and figures: 14 Word count: Abstract, 248; Introduction, 560; Discussion, 1257. 15 16
منابع مشابه
Central dysmyelination reduces the temporal fidelity of synaptic transmission and the reliability of postsynaptic firing during high-frequency stimulation.
Auditory brain stem circuits rely on fast, precise, and reliable neurotransmission to process auditory information. To determine the fundamental role of myelination in auditory brain stem function, we examined the evoked auditory brain stem response (ABR) from the Long Evans shaker (LES) rat, which lacks myelin due to a genetic deletion of myelin basic protein. In control rats, the ABR evoked b...
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